Selected publications:

• An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer.

  Li J*, Choi PS*, Chaffer CL, Labella K, Hwang JH, Giacomelli AO, Kim JW, Ilic N, Doench JG, Ly SH, Dai C, Hagel K, Hong AL, Gjoerup O, Goel S, Ge JY, Root DE, Zhao JJ, Brooks AN, Weinberg RA, Hahn WC.

  Elife. 2018 Jul 30; 7.

  
  
• Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers.

  Zhang X*, Choi PS*, Francis JM*, Imielinski M, Watanabe H, Cherniack AD, Meyerson M.

  Nature genetics. 2016; 48(2):176-82.

  
  
• Targeted genomic rearrangements using CRISPR/Cas technology.

  Choi PS, Meyerson M.

  Nature communications. 2014; 5:3728.

  
  
• Addiction to multiple oncogenes can be exploited to prevent the emergence of therapeutic resistance.

  Choi PS, Li Y, Felsher DW.

  PNAS. 2014; 111(32):E3316-24.

  
  
• Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction.

  Choi PS*, van Riggelen J*, Gentles AJ, Bachireddy P, Rakhra K, Adam SJ, Plevritis SK, Felsher DW.

  PNAS. 2011; 108(42):17432-7.

  
  
  *equal contribution
  
  

Other publications:

• Somatic Superenhancer Duplications and Hotspot Mutations Lead to Oncogenic Activation of the KLF5 Transcription Factor.

  Zhang X, Choi PS, Francis JM, Gao GF, Campbell JD, Ramachandran A, Mitsuishi Y, Ha G, Shih J, Vazquez F, Tsherniak A, Taylor AM, Zhou J, Wu Z, Berger AC, Giannakis M, Hahn WC, Cherniack AD, Meyerson M.

  Cancer discovery. 2018; 8(1):108-125.

  
  
• MET Exon 14 Mutation Encodes an Actionable Therapeutic Target in Lung Adenocarcinoma.

  Lu X, Peled N, Greer J, Wu W, Choi P, Berger AH, Wong S, Jen KY, Seo Y, Hann B, Brooks A, Meyerson M, Collisson EA.

  Cancer research. 2017; 77(16):4498-4505.

  
  
• BIM mediates oncogene inactivation-induced apoptosis in multiple transgenic mouse models of acute lymphoblastic leukemia.

  Li Y, Deutzmann A, Choi PS, Fan AC, Felsher DW.

  Oncotarget. 2016; 7(19):26926-34.

  
  
• MYC through miR-17-92 suppresses specific target genes to maintain survival, autonomous proliferation, and a neoplastic state.

  Li Y, Choi PS, Casey SC, Dill DL, Felsher DW.

  Cancer cell. 2014; 26(2):262-72.

  
  
• A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events.

  Brooks AN, Choi PS, de Waal L, Sharifnia T, Imielinski M, Saksena G, Pedamallu CS, Sivachenko A, Rosenberg M, Chmielecki J, Lawrence MS, DeLuca DS, Getz G, Meyerson M.

  PloS one. 2014; 9(1):e87361.

  
  

Link to complete list of publications